C.G.B wall

20th November 2024

We are mote than pleased to be one of 26 laboratories from 12 institutions in the Milan area supporting the RNA salon , or meetings fully dedicated to discuss new findings on RNA biology and its future! The RNA salon will be the special chance for young scientists willing to contribute to this exciting field of research in the upcoming years! A special thanks to Ivano Legnini @ Human Technopole that made this possible!

11th September 2024

We spent three days catching up on the spatial biology of cancer with top-notch scientists, early and late career ones. We learnt a lot about spatial omics, generative AI, and modern pathology. Great feeback from all partecipants. It was really a blast! Thanks to the best co-organizer Prof Francesca Ciccarelli and Prof Maria Secrier @ the Francis Crick Institute in London!

11th September 2024

Really grateful to be part of this exciting and collaborative research on KRAS G12C adaptive resistance and therapy. Kudoz goes to Prof. Chiara Ambrogio and Prof. David Santamaria

26th March 2024

If you want to catch up on the spatial biology of cancer with top-notch scientists and learn all about spatially resolved data doing an hackathon please register to this EMBO Workshop that we have the pleasure to organize with Prof Francesca Ciccarelli and Prof Maria Secrier @ the Francis Crick Institute in London!
To register go on the official EMBO page here

1st December 2023

HThe Italian Association for Cancer Research, aka AIRC fundation, will support our studies on RNA processing in pediatric and adult cancers through the BRIDGE funding scheme! A big thanks to AIRC and all the people whose generosity supports the fundation.

10th October 2023

Here we go again! Our third CGB lab retreat in Varenna! We spent a couple of days in our beloved Villa Monastero (Varenna, LC) discussing science and having fun with our mates of the Pozzoli lab @ IRCCS Medea!

5th November 2022

We presented our work of FOXA1-mediated regulation of mRNA processing using long-read sequencing data at the Oxford Nanopore Cancer Research Seminar 2022 in Florence!

More news to come!

15th November 2022

Serena and Francesca partecipated our work on pediatric sacorma tanscriptiomes at the annual meeting of Connective Tissue Oncology Society (CTOS) in Vancouver, Canada!

10th October 2022

Our lab partecipated to the annaual meeting of the Italian Association of Pediatric Oncology and Hematology (AIEOP). Serena gave her first offical oral presentation discussing novel strategy to apply RNA therapy to sacormas. Well done Serena!!

06th October 2022

We spent three days in the beatuful location of Villa Monastero (Varenna, LC) discussing science and having fun with friends from the Naccarati lab @ IIGM and the Pozzoli lab @ IRCCS Medea.

27th September 2022

Here we finally show that FOXA1 shapes mRNA production of prostate cancer. We show how these process reduce the heterogenety of transcriptomes and influcence prognosis of prostate cancer patients. Check it out!

10th July 2022

Our lab partecipated to the SIBBM conference on "The RNA World 3.0" presenting posters on three projects. Francesca with RNAmars was awarded for the best poster! Well done!

More news to come!

01st May 2021

Here our review on learning approaches for the analysis of large-scale RNA-sequencing datasets in cancer.
We present the major solutions to disentangle tumor heterogeneity of transcriptome profiles for an effective improvement of patient management, check it out!

25th April 2021

Together FPO-IRCCS Candiolo units, we are actively monitoring the evolution of SARS-CoV-2 in Piedmont, Italy. The lab is mapping the virus lineages that are circulating in the region. Here some updates!

27th September 2020

Mariachiara, a very talented intership student, left the lab to complete her education at the University of Milan. We had lots of fun with Mariachiara and she opened our road to RNA methylation! Good luck MC!

13th September 2020

In the horrible pandemic time the lab did not stop. We were lucky and determined enough to smartly work on our research projects.

18th January 2020

Have a look at our interview on AIRC Instagram account. #CancerReseach

31st December 2019

We introduced a probabilistic modelling, namely GSECA, to identify altered biological process relevant for complex phenotypes from heterogeneous high-volume RNA-seq data.

Have a look at our pancancer analysis of PTEN loss and its role in modulating immune-related processes across cancer types!

15th July 2019

Great collaboration with Francesca Ciccarelli's lab! We contribute to the implementation of a machine learning algorithm to identify cancer genes in individual patient affected by esophageal adenocarcinoma.

Last updated 1st Aug 2019

Thanks to the ISMB and Contra, and the organizers, for having me as part of the great session of Computational Oncology – Heterogeneity and Immune Defence. Inspiring discussions with Maria Scrier, Nicholas McGranahan, Giovanni Ciriello and all the other speakers!

Last updated 16th July

C.G.B. and IIGM are now relocating at the FPO IRCCS Candiolo Cancer Institute.

Last updated 1st July 2019

Serena presented GSECA at the BITS meeting in Palermo. This was the first offical presentation of our, and her, novel paradim to handle heterogeneity of high-volume RNA-seq data. Less is more!

Last updated 1st July 2019

Marco presented our first work on trascriptional regulation of RNA binding proteins in prostate cancer at the BITS annual meeting in Palermo! Well done!

Last updated 16th June 2019

Our free single-cell workshops reaches more than 200 partecipants!